|
KMID : 0359819930220050628
|
|
Journal of Korean Neurosurgical Society
1993 Volume.22 No. 5 p.628 ~ p.633
|
|
|
Prognosis of the Parenchymal Brain Metastasis According to Primary-to-Metastatic Interval
|
|
임정빈
황용순/문재곤/김한규/이화동
|
|
|
Abstract
|
|
|
The authors analyzed and compared three prognostic factors of the intraparenchymal metastatic brain tumors, regardless of therapeutic modalities, to evaluate the value of time-interval between diagnosis of primary cancer and brain metastasis as a
prognostic factor. Out of the 109 patients of metastatic brain tumor admitted to Kosin Medical College from 1984 to 1991. 93 patients were included in this retrospective study. The survival time of these patients was statistically evaluated
according to
each prognostic factor. The results were as follows. Patients with mild or no neurological deficits and patients with moderate neurological deficits showed longer survival than the patients with severe neurological deficits (P<0.01).
The presence of systemic metastasis at the time of diagnosis also significantly shortened overall survival (P<0.0095). Primary-to-metastatic interval did not significantly affect overall survival (P<0.6164). but the patients with brain metastasis
detected within 1 year after diagnosis of the primary cacer had a longer median survival than those detected after 1 year (p<0.001).
We conclude that the primary-to-metastatic interval is not valuable as a prognostic factor for intraparenchymal metastatic brain tumor, and further prospective study tailored to each specific condition will be needed for more accurate evaluation
of
prognostic factors.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
 
|